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Central administration of palmitoylethanolamide reduces hyperalgesia in mice through inhibition of NF‐κB nuclear signalling in dorsal root ganglia. Eur J Pharmacol‐acylethanolamines (NAEs), endogenous biologically Energetic lipids including the endogenous cannabinoid receptor ligand anandamide and also the satiety issue oleoylethanolamide. PEA